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ROS overproduction-induced oxidative stress represents a principal mechanism of endothelial cell death, with ROS activating multiple pathways leading to endothelial cell demise

Take 2 capsules if necessary

10.1007/s00253-021-11622-2 112 DobbsS

According to the authors, other reported complications of coffee enemas include: thermal burns from heated coffee enemas stricture, which is an area of narrowing within the intestines bowel perforation Considerations Before considering a coffee enema, people should familiarize themselves with the potential risks of the procedure

doi: 10.1016/j.actbio.2022.10.008 154 HongKCaoJJiangWDengWHuangGHuangTet al