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One 2022 review of studies in Frontiers in Nutrition on berberine supplementation for adults with cardiovascular disease risk found that supplementing it reduced weight and body mass index (BMI), as well as other metrics like cholesterol and blood pressure

Second, GPER has complex and inconsistent functions in different diseases, with varying roles in different cancers and notable sex-specific differences

"It's something that, unfortunately, is not going to go away unless we really do everything that we can," Rittenberg said

* Correspondence: Vishwanath Venketaraman, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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