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The Bottom Line Sermorelin, CJC-1295, ipamorelin, and BPC-157 each represent distinct classes of compounds with different mechanisms, half-lives, targets, and evidence bases

Unlike deficiency states, which produce well-characterised neurological and haematological symptoms, there is no clearly defined clinical syndrome associated with B12 excess from supplementation alone

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It has also been reported that sex steroids influence not only growth hormone secretion but also the local synthesis of insulin-like growth factor-I in target tissues and the expression of the growth hormone receptor in various other tissues (4)