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Although ROS play essential roles in the maintenance of basal cellular activities such as chondrocyte proliferation and matrix remodeling in cartilage, excessive oxidative stress causes detrimental events such as cellular senescence 36,121 , dedifferentiation 122 , and apoptosis 123

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It is a generic name for a variety of compounds such as L-carnitine, acetyl-L-carnitine, and propionyl-L-carnitine