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This is particularly true for those who were severely B12 deficient

However, the relatively limited number of clinical trials on synbiotic therapies in IBS patients have thus far produced varying results which could be due to the different probiotic and prebiotic components used in different trials, as well as the different subsets of IBS patients studied (Harris and Baffy, 2017)

After incorporation of their suggestions and approval, validated questionnaire using Google form was circulated through WhatsApp to practicing dermatologists and post-graduate dermatology residents in India

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