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Who should avoid: Patients with uncontrolled hypertension Those with significant cardiovascular disease (relative caution) Patients taking other medications that affect heart rate or blood pressure Monitoring: Blood pressure and heart rate should be monitored during treatment, particularly during titration

Considering the short half-life of small molecule oral GLP-1 receptor agonists, perhaps approaches to increase the duration of small molecules with a modified-release formulation may lead to improvements in long-term cardiovascular benefits

MPG: Visualization, Conceptualization, Writing review & editing, Methodology, Investigation, Writing original draft

Vitamin C often has a shelf life of one to two years, but may degrade more quickly when exposed to air and light

A better approach- instead of focusing solely on calories, consider: The quality of your food choices How different foods affect your blood sugar The timing of your meals Your bodys unique way of processing nutrients