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8 The impending entry of generics in 2026, the legislative pressure of the IRA, and the pricing caps introduced by the Trump administration signify the end of the uncontested era for GLP-1 blockbusters

Taken together, these preclinical data support interventions that target UA to counteract oxidative stress in the ischemic penumbra and protect endothelial cell function after cerebral ischemia-reperfusion injury

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Examples include ADHD stimulants like methylphenidate (Ritalin) or amphetamine salts (Adderall), which can improve focus and working memory in patients (and are sometimes misused by healthy individuals)

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