According to a 2024 PMC cardiovascular outcomes study, SGLT2 inhibitors reduce: Risk of cardiovascular death or heart failure hospitalization by 23% Risk of kidney disease progression by 45% Blood pressure by 35 mmHg systolic Body weight by 23 kg on average For Indian diabetic patients who already have some of the highest rates of heart disease in the world these numbers are extremely significant

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Affinity of 1-aminoadamantanes for the binding site in post-mortem human frontal cortex