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The guinea pigs were housed in standard plastic cages on sawdust bedding in an air-conditioned room at 221C and a 12:12h dark:light cycle

Rosenstock J, Brazg R, Andryuk PJ, Kaifeng L, Stein P, for the Sitagliptin Study 019 Group

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Following the acquisition of each MS2 spectrum, synchronous precursor selection (SPS) enabled the selection of up to 10 MS2 fragment ions for MS3 analysis