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NIH researchers reported Friday that semaglutide's weight-loss effects in the brain depend on cyclic AMP signaling inside a small population of hindbrain neurons, and that some neurons sustain that signal while others let it fade

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2E ) showed significant reductions in binge-like drinking, with no significant sex differences in efficacy: males (64.516.9%) versus females (77.214.9%) relative to vehicle (t 18 =0.56, P=0.581

Viral plasmid constructs were confirmed by Sanger sequencing

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