In animal models of heart failure induced by high-frequency pacing, ischaemia, and obesity, GLP-1RAs inhibit left ventricular remodelling and improve left ventricular contractility and diastolic function through anti-inflammatory effects, cardiomyocyte apoptosis inhibition, and glucose metabolism enhancement in cardiomyocytes [38,39,40]
Warnings and Precautions 5.1 Risk of Thyroid C-cell Tumors Liraglutide causes dose-dependent and treatment-duration-dependent thyroid C-cell tumors (adenomas and/or carcinomas) at clinically relevant exposures in both genders of rats and mice [see Nonclinical Toxicology (13.1)]
Profits Skyrocket : By retaining such a significant portion of the rebates they negotiated, traditional PBMs make a huge profit
This means GLP-1 is influencing much more than just blood sugarits interacting with reproductive organs too
For patients whove been priced out, that number sounded like relief