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After forced suppression of both isoenzymes (mutant and wild-type) through CRISPR-deletion of a regulatory molecule, HuR, stable reconstitution of wtIDH1 had a far greater effect on tumor proliferation mtIDH1 expression ( 24 )

Many foods are a natural source of B 12 because of bacterial symbiosis

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To minimize the confounding effect produced by circadian rhythm, it is crucial to execute this procedure for the same mice at the same time point every day for three days