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About this article Cite this article Chaudhary, D., Agarwal, H., Mishra, A

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The sequence of human MRP1 was then threaded on the structure of Na-Atm1 using default parameters of the program MODELLER 63

This suggests that the dose-escalation schedule used for the 36 mg arm may have been somewhat better optimized to mitigate nausea than the schedule for the 12 mg arm, or that the higher dose groups achieved better gastrointestinal adaptation during the titration period

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