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Retatrutide for the Treatment of Obesity, Obstructive Sleep Apnea and Knee Osteoarthritis: Rationale and Design of the TRIUMPH Registrational Clinical Trials

Nat Commun 11 , 869 (2020)

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While there is not much doubt that traumatic disc herniation can occur in a degenerated segment, 5 and, although documented in biomechanical in-vitro studies, 39 the existence of an isolated annulus fiber rupture with NP herniation caused by a single traumatic event without (proven) pre-existing DD is still debated in the clinical literature

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