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In preclinical models, an adequate supply of choline is essential for the assembly and secretion of VLDL from the liver, a process that exports triglycerides and prevents their intracellular accumulation

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77,174,175 Of note, GFAP expressed by reactive astrocytes following TBI, or released by damaged or dead astrocytes, can be also detected in the blood and spinal fluid, and the levels of GFAP in these fluids can reflect the severity of trauma and can be used as a diagnostic clinical tool

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