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Protective effect of GLP-1 analog liraglutide on podocytes in mice with diabetic nephropathy

Fino2 initiates ferroptosis through gpx4 inactivation and iron oxidation

Altered lipid metabolism serves as a crucial pathogenic mechanism in DKD, potentially intertwined with cellular ferroptosis, lipophagy, lipid metabolism reprogramming, and immune modulation of gut microbiota (thus impacting the liver-kidney axis)

The announcement builds on work Cigna has already done through its EncircleRx product, which was launched under its Express Scripts unit in response to the challenges clients faced around the GLP-1 class