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With 8,847 participants over eight randomized controlled trials (RCTs), it was shown that 375 out of 1,000 people lost 10% of their body weight over the course of two years, with a net benefit probability of 0.91 in the second year and 0.97 in the first

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Its the same reason why doctors dont prescribe us magnesium over prescription stool softeners, weight-bearing exercise instead of calcium injections for osteoporosis, or diet changes instead of cholesterol-lowering medication to prevent heart disease

research grant from Astellas, Bayer, Boehringer Ingelheim Japan, Fuji, Mochida, and Novartis

Meeting the clinical criteria is the first step