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Furthermore, CB-839 increased the radiosensitivity of head and neck squamous carcinoma (HNSCC) and NSCLC cells both in vitro and in a xenograft mouse model by abolishing GSH synthesis 47,48 , making it useful for concurrent chemotherapy and radiotherapy in a clinical setting

In collaboration with Eli Lilly, Regeneron has conducted Phase 2 clinical trials to evaluate whether their Trevogrumab can maintain weight loss by increasing muscle mass

Solheim, S.A

SGLT-2 inhibitors beyond diabetes: a new frontier in cancer treatment