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PMID: [PubMed] [Google Scholar] 71.Massa P, Coccia G, et al

Green Tea Epigallocatechin 3-Gallate Accumulates in Mitochondria and Displays a Selective Antiapoptotic Effect Against Inducers of Mitochondrial Oxidative Stress in Neurons

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Second, receptor selectivity Melanotan 1 has relative MC1R selectivity with minimal central activity, while Melanotan 2 activates MC1R, MC3R, and MC4R with high affinity producing both peripheral melanogenic and strong central nervous system effects simultaneously