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57 Budak et al 58 found that exenatide increased the antioxidant capacity of human monocytes/macrophages in vitro, reducing oxidative stress by decreasing the expression of ROS-producing NADPH oxidase, increasing the expression and activity of superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px), and decreasing ROS and malondialdehyde (MDA) levels

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