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In adipose tissue, we observed that CI respiration was rhythmic across gWAT and iWAT, and was reduced by Bmal1 loss, whereas respiration through CIICIV was not affected by loss of the clock

Last updated June 3, 2026 Editorial policy A Weight-Loss Drug With an Unexpected Benefit If youve been anywhere near the news in the past two years, youve heard of GLP-1 receptor agonists drugs like Ozempic, Wegovy, and Mounjaro that have transformed weight loss and diabetes management

Rabbit studies of collagenase-induced osteoarthritis report that intra-articular AOD-9604 injections improved cartilage histology and reduced lameness, with the strongest effect when combined with hyaluronic acid

Anti-malarial agent artesunate inhibits TNF-alpha-induced production of proinflammatory cytokines via inhibition of NF-kappaB and PI3 kinase/Akt signal pathway in human rheumatoid arthritis fibroblast-like synoviocytes

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