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TB-500 appears to influence angiogenesis (new blood vessel growth), cell migration, and tissue repair in animal models

Such CPP/cargo complexes have been studied for their potential applications in the diagnosis and treatment of human diseases at basic and preclinical levels, predominantly directed at the therapy of inflammation, cancer, diabetes, central nervous system (CNS) disorders, and ocular and otologic disorders (Xie et al., 2020)

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PGP is a stabilising motif derived from biological observation: it resists most endopeptidases and aminopeptidases thanks to rigid prolines (pyrrolidine cycle)