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The Canadian Drug Agency assessed Wegovy's cost-effectiveness in July 2025 and recommended a price reduction, and December 2025 negotiations between the pan-Canadian Pharmaceutical Alliance and Novo Nordisk concluded without agreement [Source: ogaei.ca/blog/wegovy-cost-in-canada/]

Similarly, in a pilot randomised trial for binge-eating disorder, liraglutide produced greater weight loss than placebo, but reductions in objective binge episodes and binge remission did not differ significantly between groups, suggesting that weight loss and binge-eating improvement may not always change in parallel (105)

As the body sheds pounds and reshapes, its completely normal for the skin and underlying tissues to change as well, sometimes resulting in loose or lax skin

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