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The principal threonine catabolizing pathway in humans involves a glycine-independent serine/threonine dehydratase (also known as serine dehydratase/threonine deaminase) yielding ammonium ion (NH 4 + ) and -ketobutyrate (also referred to as 2-ketobutyrate or 2-oxobutyrate)

It was first synthesized and studied by Sikiric and colleagues at the University of Zagreb in the 1990s, almost entirely in rodent and small-animal models.[7] The theoretical relevance to PCOS centers on three preclinical properties: reduction of systemic and gut inflammation, promotion of angiogenesis and tissue healing, and modulation of dopaminergic and serotonergic signaling

are supported by the Italian Ministry of HealthRicerca Corrente to IRCCS MultiMedica

One way to do this is by incorporating avocado into our diet

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