Nausea is the most frequently reported adverse effect, potentially affecting thirty to forty percent of patients at some point during treatment, though the intensity typically diminishes over time as tolerance develops
Class I odorant receptors, TAS1R and TAS2R taste receptors, are markers for subpopulations of circulating leukocytes
Moreover, consuming sugary snacks and processed foods can lead to leptin and insulin resistance
Both estrogen and GLP-1 receptor agonists independently reduce the production of pro-inflammatory cytokines and improve the balance between oxidative damage and antioxidant defense
Under iron overload, astrocytes exhibit markedly increased CD47 expression, reinforcing a pathological loop of immune escape, persistent activation, and inflammatory spread (Pape et al., 2021)