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GLP-1 Receptor Agonists: Mechanisms of Action and Current Indications GLP-1 is an incretinic hormone of 30 amino acids whose action is mediated by a specific receptor (GLP-1 receptor, GLP-1R) located in the bowel (distal ileum and colon), in the pancreatic alpha and beta cells and in the central nervous system (CNS) [18]

[DOI] [PMC free article] [PubMed] [Google Scholar] 42.Sisley S., Gutierrez-Aguilar R., Scott M., DAlessio D.A., Sandoval D.A., Seeley R.J

2019;9 doi: 10.1038/s41598-019-47216-2

If immediate transition is not feasible, establish an appropriate monitoring plan while continuing shared decision-making

Reference Mozaffarian, D., Agarwal, M., Aggarwal, M., et al