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Common side effects include gastrointestinal symptoms (nausea, vomiting, diarrhoea) that typically diminish during dose escalation

Great Potential in the Treatment of Metabolic Diseases With the high prevalence of metabolic diseases worldwide, 5-amino-1-methylquinolinium has shown outstanding performance in animal models of obesity, glucose metabolism disorders, fatty liver disease and other conditions

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Conversely, point estimates for tirzepatide showed a potential modest advantage for heart failure endpoints, with CIs compatible with no difference, consistent with recent data supporting protective effects of semaglutide and tirzepatide on heart failure outcomes and a potential incremental benefit with the latter 22

Mounjaro's FDA approval is for type 2 diabetes, not chronic weight management