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Heavy drinking, as defined by the Mayo Clinic, is having more than three drinks a day for women and men over 65, and more than four drinks per day, or more than 14 drinks a week for men younger than 65

Earlier shorter trials reported small statistically significant differences but the effect sizes were modest

Cartilage degeneration was scored using the Yoshimi scale, which ranges from 0, defined as normal cartilage, to 5, defined as complete loss of cartilage

Here are the primary mechanisms behind its regenerative effects: 1

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