"This research shows that alpha cells are more flexible than we imagined," said Campbell, an associate professor in the Division of Endocrinology in the Department of Medicine and a member of the Duke Molecular Physiology Institute
They suggest that future studies should investigate how cumulative drug exposure, peak drug concentrations, and treatment adherence contribute to cardiovascular protection, as well as whether GLP-1 signaling in cardiac and epicardial adipose tissues plays a direct role
Side effects often peak at this dose increase, possibly because it represents the largest percentage jump in the escalation (a 50% increase from 5 mg to 7.5 mg)
[DOI] [PMC free article] [PubMed] [Google Scholar] 117.Li G, Zhang P, Wang J, et al
Whilst current evidence does not establish a definitive link between Wegovy and suicidal ideation, any such thoughts must be taken seriously and assessed promptly by healthcare professionals who can provide appropriate support and determine whether continuing the medication is advisable