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They use pharmaceutical-grade ingredients, maintain sterile compounding environments (clean rooms), follow USP standards, and undergo regular inspections

The substance demonstrates potential as a new treatment target because it has both anti-inflammatory properties and the ability to protect cartilage from damage

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A few commenters indicated that the median, 10th percentile, and 90th percentile allowed amounts need to be interpreted in the context of the number of cases (or quantities) for which each procedure is performed and that disclosing the count of allowed amounts would help MRF users establish the credibility of this data, while further noting the policy aims to improve the accuracy and usability of the pricing data that hospitals must report