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GLUCOSE-DEPENDENT INSULINOTROPIC POLYPEPTIDE GLP-1 is a peptide hormone secreted by intestinal enteroendocrine L-cells, specific neurons of the solitary tract in the brainstem and some -cells in the pancreas [28]

The natural pathogenesis of HIV consists of three stages: 1) the primary HIV infection phase, 2) the asymptomatic chronic phase, and 3) the late HIV symptomatic phase, which leads to an immunocompromised state resulting in increased susceptibility to opportunistic infections

PMID 39963574

Liraglutide Liraglutide, an analog of human GLP- 1, is given once daily by subcutaneous injection and is resistant to the inactivation by dipeptidyl peptidase- 4 (DPP- 4) [91]

The authors concluded that regenerative biomaterial application either with growth factors or barrier membranes in combination with papilla preservation flaps should be considered the treatment of choice for residual pockets with deep intrabony ( 3 mm) defects