Dixon's group demonstrated that the GSH exporter MRP1 sensitizes HPA1 erastin-treated cells to ferroptosis and concordantly, MRP1 inhibition leads to a retention of GSH and leads to ferroptosis resistance (58)
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Throughout the remainder of the article, we will refer to this enzyme as MS
It's not every day that a molecule made of just three amino acids becomes the subject of more than a hundred research papers, gets featured in longevity podcasts, and lands on the ingredient list of luxury skincare brands sold in dermatology clinics around the world
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