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doi:10.1016/j.clnu.2016.06.014

Furthermore, targeted ophthalmic trials utilizing T4-based eye drops (such as the RGN-259 formulation) have demonstrated safety and clinical efficacy in treating severe dry eye conditions, bacterial corneal infections, and physical corneal wounds

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Because this effect was not statistically different from the neutral effects on nonfatal MI associated with the GLP-1RA class, we make no recommendation on the basis of this end point