Firstly, although we defined our inclusion criteria for anti-diabetic drug-nave patients as those who had not received any antidiabetic medication for at least three months (12 weeks), there might be some heterogeneity
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Tirzepatide dose steps and why side effects change at each increase Both Mounjaro and Zepbound follow the same six-step schedule: 2.5 mg weekly for four weeks (tolerability only), then 5 mg, 7.5 mg, 10 mg, 12.5 mg, and 15 mg at minimum four-week intervals
Layer P, Peschel S, Schlesinger T, and Goebell H
