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With regard to pregnancy, breastfeeding or any serious condition, only a healthcare professional can advise

doi: 10.3389/fnagi.2022.815347 60 HabasA.HahnJ.WangX.MargetaM

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NNMT inhibition increases cellular concentrations of both substrates that the enzyme would otherwise consume: SAM (the universal methyl donor) and nicotinamide (the NAD + salvage precursor)

Biochemistry 40:168893, PMID: 11327828 Marshall HE, Hess DT, Stamler JS (2004) S -nitrosylation: physiological regulation of NF-kappaB