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Methods: The number of hospital discharges from 2012 to 2022 was analyzed, selecting patients with hepatitis C as primary or secondary diagnosis

It is noteworthy that the lipid peroxidation and metabolic disorders of intracellular LOOHs are mainly related to iron metabolism (Figure 1B), glutathione (GSH)-dependent pathway (Figure 1C), and coenzyme Q 10 (CoQ 10 )-dependent pathway (Figure 1D)

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doi: 10.3389/fped.2014.00066 Received 09 May 2014 Accepted 09 June 2014 Published 27 June 2014 Volume 2 - 2014 Edited by Roberto Canitano, University Hospital of Siena, Italy Reviewed by Andrew Walter Zimmerman, Harvard Medical School, USA

Evaluation of a murine liver colonization model revealed that PKLR promotes cell survival in the tumor core during conditions of high cell density and oxygen deprivation by increasing glutathione, the primary endogenous antioxidant