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In vivo , patient-derived xenografts (PDXs) and syngeneic mouse models have also demonstrated that CPEB3 depletion inhibits tumour growth and metastasis, as well as facilitating pharmacokinetics, bioavailability and lack of systemic toxicity evaluations prior to human testing which are invaluable safety and efficacy details (222)

AA: Investigation, Resources, Conceptualization, Validation, Writing review & editing, Visualization, Data curation, Writing original draft

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Zhang XW, Zhang XQ, Liang SL, Ye YR, Lin Y (2013) Key regulatory elements of a strong constitutive promoter, P- , from GCW14 Pichia pastoris