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Reactivity, in biological systems, is almost inevitably associated with toxicity, and ROS can damage various biological molecules: lipids (causing lipid peroxidation and membrane damage), DNA (causing DNA breaks), and proteins (causing, for instance, oxidation of various amino acids and inactivation of essential enzymes)

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Benedetti F, Poletti S, Radaelli D et al (2010) Temporal lobe grey matter volume in schizophrenia is associated with a genetic polymorphism influencing glycogen synthase kinase 3 activity

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