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Up to one in three participants on semaglutide 7.2 mg achieved at least 25% weight loss over 72 weeks Mean weight loss with semaglutide 7.2 mg reached 21%, reflecting overall treatment efficacy Up to 84% of weight loss was driven by reductions in fat mass, supporting meaningful improvements in body composition SINGAPORE, July 8, 2026 /PRNewswire/ -- Novo Nordisk announced an update to the Singapore label for semaglutide, approved in Singapore as Wegovy (semaglutide) injection, incorporating clinical evidence from the STEP UP trial in adults living with obesity without diabetes

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Clinical trials report an average of 20.9% body weight loss with the maximum dose

Such a strategy is followed, for example, with the long-acting antipsychotic injection paliperidone palmitate