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The flux through pathways that require nonesterified CoA, such as the oxidation of glucose, may be reduced if all the CoA available in a given cell compartment is esterified

In other words, its the hormonal version of your best friend who says, Are you sure you want dessert? Accidental Breakthrough Fast forward to the 2000s

It also acts on appetite regulation pathways in the brain, which may support weight reduction as part of comprehensive diabetes management

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It supports cellular migration and organization during repair, which is why it is commonly used as a model compound in wound-healing and regenerative research