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Furthermore, the revelation that impeding the glutamine metabolism of cancer cells could enhance the immune microenvironment and bolster the effectiveness of immunotherapy has provided a compelling impetus for further exploration [15]

The predicted translated sequence of the PbGST protein was identical to the one available at PlasmoDB (PBANKA_102390) and was used to generate the 3D structural homology model

High levels of HO inactivate protective peptides like ACTH and -MSH, while decreasing enzyme activities like methionine sulfoxide reductase, consequently intensifying oxidative damage and accelerating melanocyte death 46