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Foundational Research The foundational work in the 1980s by researchers including Guillemin, Rivier, and others established that synthetic GRF(1-29)-NH2 (Sermorelin) possesses full biological activity for stimulating GH release equivalent to the full 44-amino acid GHRH, validating the concept that only the N-terminal 29 amino acids are required for receptor binding and activation

Nature 437 , 13701375 (2005)

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We observed that maternal SD during pregnancy led to significant changes in serum hormone levels