Among these, bortezomib is a proteasome inhibitor that induces ROS and ER stress in head and neck squamous cell carcinoma cells 112 , and celecoxib, a nonsteroidal anti-inflammatory drug, aggravates ER stress and induces apoptosis by altering the Bax/Bcl-2 ratio and increasing ROS in prostate cancer cells 113
Legras JL, Moreno-Garcia J, Zara S, Zara G, Garcia-Martinez T, Mauricio JC, Mannazzu I, Coi AL, Bou Zeidan M, Dequin S, Moreno J, Budroni M (2016) Flor yeast: new perspectives beyond wine aging
Most Abundant Intracellular Antioxidant: Glutathione is the most abundant antioxidant produced within cells, present in millimolar concentrations in most tissues
Demonstrated this in a 1998 study showing that ipamorelin released GH in a dose-dependent manner in swine without elevating cortisol or prolactin at doses up to 1 mg/kg [1]
Zou and others showed that glucosinolate and xanthotoxin present in Brassica juncea stimulated the expression of GSTE1 in the midgut of Spodoptera littoralis larvae after feeding