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DHODH holds a pivotal position in the biosynthetic pathway of pyrimidine nucleotides, playing a crucial role in the production of DNA and RNA (49), Inhibition of DHODH disrupts this pathway, leading to abnormalities in, or cessation of, pyrimidine nucleotide synthesis

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Oncotarget (2017) 8(15):2411929

Healthcare providers should think about using other methods like ultrasound or MRI that are safer for the kidneys, especially for patients who have diabetes