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Detailed views of boxed regions show that W297 and R299 in the active GLP-1R structure adopt similar orientations compared to the equivalent residues in CRF 1 R

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One study utilized transgene delivery of the unexpanded copy of the FMR1 gene using an AAV vector directly injected into the brains of the Fmr1 -/- mice, and this successfully rescued repetitive behavioral, social and seizure mouse phenotypes [47]