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3.3 Trimethylamine-N-oxide is a marker of renal impairment and a renal toxin Since the kidney is the primary site of TMAO elimination from the body ( 2 ) and with poor prognosis in patients with CKD (Tang et al., 2015b)
Today, we are no longer in that scenario, but the debate about this type of medicine ranges from the health side (perhaps the strongest point) to the social side, because the fact that it works does not mean that it is reaching everyone
44 Thus, apart from tumor thickness greater than 5 mm and the presence of lymphovascular invasion, many of the histologic prognostic parameters of cutaneous melanoma (i.e., Breslows classification and Clarks level of invasion) do not apply to oral melanoma
