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GLP-1s are not controlled substances, she said

When semaglutide, tirzepatide, and other GLP-1 receptor agonists cause fluid and electrolyte losses through gastrointestinal side effects, or when reduced food intake limits your natural electrolyte consumption and/or water intake via food, your gut function can suffer

10 BiagiottiS.AbbasF.MontanariM.BarattiniC.RossiL.MagnaniM.et al (2023)

In cirrhosis, decreased adenosine triphosphate production in muscles can cause ion channel dysfunction and destabilization of the sarcolemma, leading to prolonged muscle contractions