Muscle Loss Risk Increases (Major Concern) GLP-1 users already risk: low protein intake low calorie intake rapid weight loss lean tissue loss Add nightly alcohol and you get: impaired muscle protein synthesis lower testosterone (men) reduced growth hormone increased cortisol reduced recovery Result: More muscle loss Less fat loss Softer look Slower metabolism This is one of the biggest physiological downsides
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l Clinical observation and some preliminary studies suggest the GLP-1 medication semaglutidebetter known by brand names like Ozempic, Mounjaro, and Wegovycan reduce cravings and help individuals with alcohol use disorder reduce or stop drinking
doi: 10.1126/scitranslmed.3007218 60 AdriaenssensAEBiggsEKDarwishTTadrossJSukthankarTGirishMet al