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Participants were eligible for inclusion if they were aged between 18 and 65 years and had either a BMI 40, or a BMI 35 accompanied by obesity-related comorbidities

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For autoimmune applications, where the margin between helpful modulation and harmful stimulation may be narrow, getting these details right matters even more than in other contexts

Higher doses and more intensive protocols suit acute healing needs

In addition, captopril significantly increases the concentration of 5-HT and 5-HIAA in the parabrachial lateral nucleus (169)