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The triple-receptor mechanism is intended to produce greater and more sustained reductions in body weight and improvements in glycaemic control than single or dual agonists

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Patients should monitor their response to the medication, avoiding high-sugar or high-fat meals that may exacerbate mild side effects like nausea

Insurers like Anthem and Harvard Pilgrim excluded coverage of GLP-1s for weight loss from most of the plans they offered in 2026, and large employers that set their own coverages have largely followed suit